Entrainment by axisymmetric jets impinging on a flat plate

An experimental technique is described for the determination of the entrainment in an axisymmetric gaseous jet impinging normally on a flat plate situated below the nozzle. Typical results are given of experimental work carried out using this technique for an Rix jet flowing into a like atmosphere of similar density. These results suggest that the relationships describing the entrainment are: (a) m/mo = 0.3 hid for the axial jet, and (b) mimo = 0.6 Rid for the wall jet. It is also deduced that the growth of the *wall jet is described by the equation: 5 w r approximately. Some experimental results are given for a jet at a higher temperature than the surrounding atmosphere

Very Luminous Carbon Stars in the Outer Disk of the Triangulum Spiral Galaxy

Stars with masses in the range from about 1.3 to 3.5 Mo pass through an evolutionary stage where they become carbon stars. In this stage, which lasts a few Myr, these stars are extremely luminous pulsating giants. They are so luminous in the near-infrared that just a few of them can double the integrated luminosity of intermediate-age (0.6 to 2 Gyr) Magellanic Cloud clusters at 2.2 microns. Astronomers routinely use such near-infrared observations to minimize the effects of dust extinction, but it is precisely in this band that carbon stars can contribute hugely. The actual contribution of carbon stars to the outer disk light of evolving spiral galaxies has not previously been morphologically investigated. Here we report new and very deep near-IR images of the Triangulum spiral galaxy M33=NGC 598, delineating spectacular arcs of carbon stars in its outer regions. It is these arcs which dominate the near-infrared m=2 Fourier spectra of M33. We present near-infrared photometry with the Hale 5-m reflector, and propose that the arcs are the signature of accretion of low metallicity gas in the outer disk of M33.Comment: 4 pages, 4 figures. Revised version submitted to A&A Letter

The bloodstream differentiation - division of Trypanosoma brucei studied using mitochondrial markers

In the bloodstream of its mammalian host, the African trypanosome Trypanosoma brucei undergoes a life cycle stage differentiation from a long, slender form to a short, stumpy form. This involves three known major events: exit from a proliferative cell cycle, morphological change and mitochondrial biogenesis. Previously, models have been proposed accounting for these events (Matthews & Gull 1994a). Refinement of, and discrimination between, these models has been hindered by a lack of stage-regulated antigens useful as markers at the single-cell level. We have now evaluated a variety of cytological markers and applied them to investigate the coordination of phenotypic differentiation and cell cycle arrest. Our studies have focused on the differential expression of the mitochondrial enzyme dihydrolipoamide dehydrogenase relative to the differentiation-division of bloodstream trypanosomes. The results implicate a temporal order of events: commitment, division, phenotypic differentiation

Signature of wide-spread clumping in B supergiant winds

We seek to establish additional observational signatures of the effects of clumping in OB star winds. The action of clumping on strategic wind-formed spectral lines is tested to steer the development of models for clumped winds and thus improve the reliability of mass-loss determinations for massive stars.The SiIV 1400 resonance line doublets of B0 to B5 supergiants are analysed using empirical line-synthesis models. The focus is on decoding information on wind clumping from measurements of ratios of the radial optical depths (tau_(rad)(w)) of the red and blue components of the SiIV doublet. We exploit in particular the fact that the two doublet components are decoupled and formed independently for targets with relatively low wind terminal velocities. Line-synthesis analyses reveal that the mean ratio of tau_(rad)(w) of the blue to red SiIV components are rarely close to the canonical value of ~ 2 (expected from atomic constants), and spread instead over a range of values between ~1 and 2. These results are interpreted in terms of a photosphere that is partially obscured by optically thick structures in the outflowing gas.The spectroscopic signatures established in this study demonstrate the wide-spread existence of wind clumping in B supergiants. The additional information in unsaturated doublet profiles provides a means to quantify the porosity of the winds.Comment: Accepted for publication in A&A Letter

The age of data-driven proteomics : how machine learning enables novel workflows

A lot of energy in the field of proteomics is dedicated to the application of challenging experimental workflows, which include metaproteomics, proteogenomics, data independent acquisition (DIA), non-specific proteolysis, immunopeptidomics, and open modification searches. These workflows are all challenging because of ambiguity in the identification stage; they either expand the search space and thus increase the ambiguity of identifications, or, in the case of DIA, they generate data that is inherently more ambiguous. In this context, machine learning-based predictive models are now generating considerable excitement in the field of proteomics because these predictive models hold great potential to drastically reduce the ambiguity in the identification process of the above-mentioned workflows. Indeed, the field has already produced classical machine learning and deep learning models to predict almost every aspect of a liquid chromatography-mass spectrometry (LC-MS) experiment. Yet despite all the excitement, thorough integration of predictive models in these challenging LC-MS workflows is still limited, and further improvements to the modeling and validation procedures can still be made. In this viewpoint we therefore point out highly promising recent machine learning developments in proteomics, alongside some of the remaining challenges

Nomenclature for the chromosomes of the common shrew (Sorex araneus)

A G-band composite karyotype has been prepared for the common shrew (Sorex araneus Linnaeus, 1758). This includes multiple cut-outs of each chromosome arm (in different stages of contraction) derived from chromosome spreads prepared by a variety of methods by the different authors. The important features of each chromosome arm are described. The nomenclature for the chromosome arms follows that of Halkka et al. (1974) as clarified by Fredga, Nawrin (1977) and subsequent authors, i.e. italicised letters of the alphabet are used with a as the largest chromosome arm. Different authors have used a variety of methods to describe the karyotype of (a) individuals and (b) the pattern of variation within populations. Also, definitions of chromosomal ‘race’ differ. We suggest a standardised scheme for the description of individuals, populations and chromosomal race

Comparison of Compatibility of Streptococcus Starters in Reconstituted Nonfat Dry Milk and a Whey-Based Bacteriophage Inhibitory Medium

Compatibility of mixed cultures of Streptococcus lactis and Streptococcus cremoris we e studied by the phage tracer technique in 10% nonfat dry milk and a whey-based phage inhibitory medium. Methods of membrane dialysis and differential enumeration were tried and abandoned. Dominance occurred in nonfat dry milk and in the whey-based medium during a continuous fermentation period within a pH range 6.8 to 5.2. The dominance pattern of two-strain combinations in 10% nonfat dry milk was different from that in the whey-based media. Dominance varied from one strain to another in no consistent sequence in some combinations. Dominance patterns of combinations were compared with patterns of stimulation and inhibition